import * as t from 'io-ts';
import { IMeta } from './RTTI_Meta';
import { IElement } from './RTTI_Element';
import { INarrative } from './RTTI_Narrative';
import { IResourceList } from '../Union/RTTI_ResourceList';
import { IExtension } from './RTTI_Extension';
import { IIdentifier } from './RTTI_Identifier';
import { ICodeableConcept } from './RTTI_CodeableConcept';
import { ISubstance_Instance } from './RTTI_Substance_Instance';
import { ISubstance_Ingredient } from './RTTI_Substance_Ingredient';
export declare enum SubstanceStatusKind {
    _active = "active",
    _inactive = "inactive",
    _enteredInError = "entered-in-error"
}
import { IDomainResource } from './IDomainResource';
export interface ISubstance extends IDomainResource {
    resourceType: 'Substance';
    code: ICodeableConcept;
    id?: string;
    meta?: IMeta;
    implicitRules?: string;
    _implicitRules?: IElement;
    language?: string;
    _language?: IElement;
    text?: INarrative;
    contained?: IResourceList[];
    extension?: IExtension[];
    modifierExtension?: IExtension[];
    identifier?: IIdentifier[];
    status?: SubstanceStatusKind;
    _status?: IElement;
    category?: ICodeableConcept[];
    description?: string;
    _description?: IElement;
    instance?: ISubstance_Instance[];
    ingredient?: ISubstance_Ingredient[];
}
export declare const RTTI_Substance: t.Type<ISubstance>;