BiologicalEntity
type: Class
subclass of: Thing
is part of: schema.biothings.io

OntologyClass
type: Class
comment: a concept or class in an ontology, vocabulary or thesaurus
subclass of: Thing
is part of: schema.biothings.io

RelationshipType
type: Class
comment: An OWL property used as an edge label
subclass of: OntologyClass
is part of: schema.biothings.io

GeneOntologyClass
type: Class
comment: an ontology class that describes a functional aspect of a gene, gene prodoct or complex
subclass of: OntologyClass
is part of: schema.biothings.io

OrganismTaxon
type: Class
subclass of: OntologyClass
is part of: schema.biothings.io

OrganismalEntity
type: Class
comment: A named entity that is either a part of an organism, a whole organism, population or clade of organisms, excluding molecular entities
subclass of: BiologicalEntity
is part of: schema.biothings.io

IndividualOrganism
type: Class
subclass of: OrganismalEntity
is part of: schema.biothings.io

Case
type: Class
comment: An individual organism that has a patient role in some clinical context.
subclass of: IndividualOrganism
is part of: schema.biothings.io

PopulationOfIndividualOrganisms
type: Class
subclass of: OrganismalEntity
is part of: schema.biothings.io

Biosample
type: Class
subclass of: OrganismalEntity
is part of: schema.biothings.io

DiseaseOrPhenotypicFeature
type: Class
comment: Either one of a disease or an individual phenotypic feature. Some knowledge resources such as Monarch treat these as distinct, others such as MESH conflate.
subclass of: BiologicalEntity
is part of: schema.biothings.io

Disease
type: Class
subclass of: DiseaseOrPhenotypicFeature
is part of: schema.biothings.io

PhenotypicFeature
type: Class
subclass of: DiseaseOrPhenotypicFeature
is part of: schema.biothings.io

Environment
type: Class
comment: A feature of the environment of an organism that influences one or more phenotypic features of that organism, potentially mediated by genes
subclass of: BiologicalEntity
is part of: schema.biothings.io

InformationContentEntity
type: Class
comment: a piece of information that typically describes some piece of biology or is used as support.
subclass of: Thing
is part of: schema.biothings.io

ConfidenceLevel
type: Class
comment: Level of confidence in a statement
subclass of: InformationContentEntity
is part of: schema.biothings.io

EvidenceType
type: Class
comment: Class of evidence that supports an association
subclass of: InformationContentEntity
is part of: schema.biothings.io

Publication
type: Class
comment: Any published piece of information. Can refer to a whole publication, or to a part of it (e.g. a figure, figure legend, or section highlighted by NLP). The scope is intended to be general and include information published on the web as well as journals.
subclass of: InformationContentEntity
is part of: schema.biothings.io

MolecularEntity
type: Class
comment: A gene, gene product, small molecule or macromolecule (including protein complex)
subclass of: BiologicalEntity
is part of: schema.biothings.io

ChemicalSubstance
type: Class
comment: May be a chemical entity or a formulation with a chemical entity as active ingredient, or a complex material with multiple chemical entities as part
subclass of: MolecularEntity
is part of: schema.biothings.io

Drug
type: Class
comment: A substance intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease
subclass of: ChemicalSubstance
is part of: schema.biothings.io

Metabolite
type: Class
comment: Any intermediate or product resulting from metabolism. Includes primary and secondary metabolites.
subclass of: ChemicalSubstance
is part of: schema.biothings.io

AnatomicalEntity
type: Class
comment: A subcellular location, cell type or gross anatomical part
subclass of: OrganismalEntity
is part of: schema.biothings.io

LifeStage
type: Class
comment: A stage of development or growth of an organism, including post-natal adult stages
subclass of: OrganismalEntity
is part of: schema.biothings.io

PlanetaryEntity
type: Class
comment: Any entity or process that exists at the level of the whole planet
subclass of: Thing
is part of: schema.biothings.io

EnvironmentalProcess
type: Class
subclass of: PlanetaryEntity
is part of: schema.biothings.io

EnvironmentalFeature
type: Class
subclass of: PlanetaryEntity
is part of: schema.biothings.io

ClinicalEntity
type: Class
comment: Any entity or process that exists in the clinical domain and outside the biological realm. Diseases are placed under biological entities
subclass of: Thing
is part of: schema.biothings.io

ClinicalTrial
type: Class
subclass of: ClinicalEntity
is part of: schema.biothings.io

ClinicalIntervention
type: Class
subclass of: ClinicalEntity
is part of: schema.biothings.io

Device
type: Class
comment: A thing made or adapted for a particular purpose, especially a piece of mechanical or electronic equipment
subclass of: Thing
is part of: schema.biothings.io

GenomicEntity
type: Class
comment: an entity that can either be directly located on a genome (gene, transcript, exon, regulatory region) or is encoded in a genome (protein)
subclass of: MolecularEntity
is part of: schema.biothings.io

Genome
type: Class
comment: A genome is the sum of genetic material within a cell or virion.
subclass of: GenomicEntity
is part of: schema.biothings.io

Transcript
type: Class
comment: An RNA synthesized on a DNA or RNA template by an RNA polymerase
subclass of: GenomicEntity
is part of: schema.biothings.io

Exon
type: Class
comment: A region of the transcript sequence within a gene which is not removed from the primary RNA transcript by RNA splicing
subclass of: GenomicEntity
is part of: schema.biothings.io

CodingSequence
type: Class
subclass of: GenomicEntity
is part of: schema.biothings.io

MacromolecularMachine
type: Class
comment: A union of gene, gene product, and macromolecular complex. These are the basic units of function in a cell. They either carry out individual biological activities, or they encode molecules which do this.
subclass of: GenomicEntity
is part of: schema.biothings.io

GeneOrGeneProduct
type: Class
comment: a union of genes or gene products. Frequently an identifier for one will be used as proxy for another
subclass of: MacromolecularMachine
is part of: schema.biothings.io

Gene
type: Class
subclass of: GeneOrGeneProduct
is part of: schema.biothings.io

GeneProduct
type: Class
comment: The functional molecular product of a single gene. Gene products are either proteins or functional RNA molecules
subclass of: GeneOrGeneProduct
is part of: schema.biothings.io

Protein
type: Class
comment: A gene product that is composed of a chain of amino acid sequences and is produced by ribosome-mediated translation of mRNA
subclass of: GeneProduct
is part of: schema.biothings.io

GeneProductIsoform
type: Class
comment: This is an abstract class that can be mixed in with different kinds of gene products to indicate that the gene product is intended to represent a specific isoform rather than a canonical or reference or generic product. The designation of canonical or reference may be arbitrary, or it may represent the superclass of all isoforms.
subclass of: GeneProduct
is part of: schema.biothings.io

ProteinIsoform
type: Class
comment: Represents a protein that is a specific isoform of the canonical or reference protein. See https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114032/
subclass of: Protein
is part of: schema.biothings.io

RnaProduct
type: Class
subclass of: GeneProduct
is part of: schema.biothings.io

RnaProductIsoform
type: Class
comment: Represents a protein that is a specific isoform of the canonical or reference RNA
subclass of: RnaProduct
is part of: schema.biothings.io

NoncodingRnaProduct
type: Class
subclass of: RnaProduct
is part of: schema.biothings.io

Microrna
type: Class
subclass of: NoncodingRnaProduct
is part of: schema.biothings.io

MacromolecularComplex
type: Class
subclass of: MacromolecularMachine
is part of: schema.biothings.io

GeneFamily
type: Class
comment: any grouping of multiple genes or gene products related by common descent
subclass of: MolecularEntity
is part of: schema.biothings.io

Genotype
type: Class
comment: An information content entity that describes a genome by specifying the total variation in genomic sequence and/or gene expression, relative to some extablished background
subclass of: GenomicEntity
is part of: schema.biothings.io

Haplotype
type: Class
comment: A set of zero or more Alleles on a single instance of a Sequence[VMC]
subclass of: GenomicEntity
is part of: schema.biothings.io

SequenceVariant
type: Class
comment: An allele that varies in its sequence from what is considered the reference allele at that locus.
subclass of: GenomicEntity
is part of: schema.biothings.io

DrugExposure
type: Class
comment: A drug exposure is an intake of a particular chemical substance
subclass of: Environment
is part of: schema.biothings.io

Treatment
type: Class
comment: A treatment is targeted at a disease or phenotype and may involve multiple drug 'exposures'
subclass of: Environment
is part of: schema.biothings.io

GeographicLocation
type: Class
comment: a location that can be described in lat/long coordinates
subclass of: PlanetaryEntity
is part of: schema.biothings.io

GeographicLocationAtTime
type: Class
comment: a location that can be described in lat/long coordinates, for a particular time
subclass of: GeographicLocation
is part of: schema.biothings.io

Occurrent
type: Class
comment: A processual entity
subclass of: Thing
is part of: schema.biothings.io

BiologicalProcessOrActivity
type: Class
comment: Either an individual molecular activity, or a collection of causally connected molecular activities
subclass of: BiologicalEntity
is part of: schema.biothings.io

MolecularActivity
type: Class
comment: An execution of a molecular function carried out by a gene product or macromolecular complex.
subclass of: BiologicalProcessOrActivity
is part of: schema.biothings.io

ActivityAndBehavior
type: Class
comment: Activity or behavior of any independent integral living, organization or mechanical actor in the world
subclass of: Occurrent
is part of: schema.biothings.io

Procedure
type: Class
comment: A series of actions conducted in a certain order or manner
subclass of: Occurrent
is part of: schema.biothings.io

Phenomenon
type: Class
comment: a fact or situation that is observed to exist or happen, especially one whose cause or explanation is in question
subclass of: Occurrent
is part of: schema.biothings.io

BiologicalProcess
type: Class
comment: One or more causally connected executions of molecular functions
subclass of: BiologicalProcessOrActivity
is part of: schema.biothings.io

Pathway
type: Class
subclass of: BiologicalProcess
is part of: schema.biothings.io

PhysiologicalProcess
type: Class
subclass of: BiologicalProcess
is part of: schema.biothings.io

CellularComponent
type: Class
comment: A location in or around a cell
subclass of: AnatomicalEntity
is part of: schema.biothings.io

Cell
type: Class
subclass of: AnatomicalEntity
is part of: schema.biothings.io

CellLine
type: Class
subclass of: Biosample
is part of: schema.biothings.io

GrossAnatomicalStructure
type: Class
subclass of: AnatomicalEntity
is part of: schema.biothings.io

molecularlyInteractsWith
type: Property
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

geneticallyInteractsWith
type: Property
comment: holds between two genes whose phenotypic effects are dependent on each other in some way - such that their combined phenotypic effects are the result of some interaction between the activity of their gene products. Examples include epistasis and synthetic lethality.
domain includes: Gene
is part of: schema.biothings.io
range includes: Gene

affectsAbundanceOf
type: Property
comment: holds between two molecular entities where the action or effect of one changes the amount of the other within a system of interest
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

increasesAbundanceOf
type: Property
comment: holds between two molecular entities where the action or effect of one increases the amount of the other within a system of interest
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

decreasesAbundanceOf
type: Property
comment: holds between two molecular entities where the action or effect of one decreases the amount of the other within a system of interest
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

affectsActivityOf
type: Property
comment: holds between two molecular entities where the action or effect of one changes the activity of the other within a system of interest
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

increasesActivityOf
type: Property
comment: holds between two molecular entities where the action or effect of one increases the activity of the other within a system of interest
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

decreasesActivityOf
type: Property
comment: holds between two molecular entities where the action or effect of one decreases the activity of the other within a system of interest
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

affectsExpressionOf
type: Property
comment: holds between two molecular entities where the action or effect of one changes the level of expression of the other within a system of interest
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: GenomicEntity

increasesExpressionOf
type: Property
comment: holds between two molecular entities where the action or effect of one increases the level of expression of the other within a system of interest
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: GenomicEntity

decreasesExpressionOf
type: Property
comment: holds between two molecular entities where the action or effect of one decreases the level of expression of the other within a system of interest
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: GenomicEntity

affectsFoldingOf
type: Property
comment: holds between two molecular entities where the action or effect of one changes the rate or quality of folding of the other
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

increasesFoldingOf
type: Property
comment: holds between two molecular entities where the action or effect of one increases the rate or quality of folding of the other
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

decreasesFoldingOf
type: Property
comment: holds between two molecular entities where the action or effect of one decreases the rate or quality of folding of the other
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

affectsLocalizationOf
type: Property
comment: holds between two molecular entities where the action or effect of one changes the localization of the other within a system of interest
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

increasesLocalizationOf
type: Property
comment: holds between two molecular entities where the action or effect of one increases the proper localization of the other within a system of interest
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

decreasesLocalizationOf
type: Property
comment: holds between two molecular entities where the action or effect of one decreases the proper localization of the other within a system of interest
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

affectsMetabolicProcessingOf
type: Property
comment: holds between two molecular entities where the action or effect of one impacts the metabolic processing of the other within a system of interest
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

increasesMetabolicProcessingOf
type: Property
comment: holds between two molecular entities where the action or effect of one increases the rate of metabolic processing of the other within a system of interest
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

decreasesMetabolicProcessingOf
type: Property
comment: holds between two molecular entities where the action or effect of one decreases the rate of metabolic processing of the other within a system of interest
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

affectsMolecularModificationOf
type: Property
comment: holds between two molecular entities where the action or effect of one leads changes in the molecular modification(s) of the other (e.g. via post-translational modifications of proteins such as the addition of phosphoryl group, or via redox reaction that adds or subtracts electrons)
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

increasesMolecularModificationOf
type: Property
comment: holds between two molecular entities where the action or effect of one leads to increased molecular modification(s) of the other (e.g. via post-translational modifications of proteins such as the addition of phosphoryl group, or via redox reaction that adds or subtracts electrons)
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

decreasesMolecularModificationOf
type: Property
comment: holds between two molecular entities where the action or effect of one leads to decreased molecular modification(s) of the other (e.g. via post-translational modifications of proteins such as the addition of phosphoryl group, or via redox reaction that adds or subtracts electrons)
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

affectsSynthesisOf
type: Property
comment: holds between two molecular entities where the action or effect of one impacts the rate of chemical synthesis of the other
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

increasesSynthesisOf
type: Property
comment: holds between two molecular entities where the action or effect of one increases the rate of chemical synthesis of the other
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

decreasesSynthesisOf
type: Property
comment: holds between two molecular entities where the action or effect of one decreases the rate of chemical synthesis of the other
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

affectsDegradationOf
type: Property
comment: holds between two molecular entities where the action or effect of one impacts the rate of degradation of the other within a system of interest
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

increasesDegradationOf
type: Property
comment: holds between two molecular entities where the action or effect of one increases the rate of degradation of the other within a system of interest
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

decreasesDegradationOf
type: Property
comment: holds between two molecular entities where the action or effect of one decreases the rate of degradation of the other within a system of interest
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

affectsMutationRateOf
type: Property
comment: holds between a molecular entity and a genomic entity where the action or effect of the molecular entity impacts the rate of mutation of the genomic entity within a system of interest
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: GenomicEntity

increasesMutationRateOf
type: Property
comment: holds between a molecular entity and a genomic entity where the action or effect of the molecular entity increases the rate of mutation of the genomic entity within a system of interest
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: GenomicEntity

decreasesMutationRateOf
type: Property
comment: holds between a molecular entity and a genomic entity where the action or effect of the molecular entity decreases the rate of mutation of the genomic entity within a system of interest
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: GenomicEntity

affectsResponseTo
type: Property
comment: holds between two molecular entities where the action or effect of one impacts the susceptibility of a biological entity or system (e.g. an organism, cell, cellular component, macromolecular machine, biological or pathological process) to the other
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

increasesResponseTo
type: Property
comment: holds between two molecular entities where the action or effect of one increases the susceptibility of a biological entity or system (e.g. an organism, cell, cellular component, macromolecular machine, biological or pathological process) to the other
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

decreasesResponseTo
type: Property
comment: holds between two molecular entities where the action or effect of one decreases the susceptibility of a biological entity or system (e.g. an organism, cell, cellular component, macromolecular machine, biological or pathological process) to the other
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

affectsSplicingOf
type: Property
comment: holds between a molecular entity and an mRNA where the action or effect of the molecular entity impacts the splicing of the mRNA
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: Transcript

increasesSplicingOf
type: Property
comment: holds between a molecular entity and an mRNA where the action or effect of the molecular entity increases the proper splicing of the mRNA
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: Transcript

decreasesSplicingOf
type: Property
comment: holds between a molecular entity and an mRNA where the action or effect of the molecular entity decreases the proper splicing of the mRNA
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: Transcript

affectsStabilityOf
type: Property
comment: holds between two molecular entities where the action or effect of one impacts the stability of the other within a system of interest
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

increasesStabilityOf
type: Property
comment: holds between two molecular entities where the action or effect of one increases the stability of the other within a system of interest
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

decreasesStabilityOf
type: Property
comment: holds between two molecular entities where the action or effect of one decreases the stability of the other within a system of interest
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

affectsTransportOf
type: Property
comment: holds between two molecular entities where the action or effect of one impacts the rate of transport of the other across some boundary in a system of interest
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

increasesTransportOf
type: Property
comment: holds between two molecular entities where the action or effect of one increases the rate of transport of the other across some boundary in a system of interest
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

decreasesTransportOf
type: Property
comment: holds between two molecular entities where the action or effect of one decreases the rate of transport of the other across some boundary in a system of interest
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

affectsSecretionOf
type: Property
comment: holds between two molecular entities where the action or effect of one impacts the rate of secretion of the other out of a cell, gland, or organ
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

increasesSecretionOf
type: Property
comment: holds between two molecular entities where the action or effect of one increases the rate of secretion of the other out of a cell, gland, or organ
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

decreasesSecretionOf
type: Property
comment: holds between two molecular entities where the action or effect of one decreases the rate of secretion of the other out of a cell, gland, or organ
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

affectsUptakeOf
type: Property
comment: holds between two molecular entities where the action or effect of one impacts the rate of uptake of the other into of a cell, gland, or organ
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

increasesUptakeOf
type: Property
comment: holds between two molecular entities where the action or effect of one increases the rate of uptake of the other into of a cell, gland, or organ
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

decreasesUptakeOf
type: Property
comment: holds between two molecular entities where the action or effect of one decreases the rate of uptake of the other into of a cell, gland, or organ
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

regulates,ProcessToProcess
type: Property
domain includes: Occurrent
is part of: schema.biothings.io
range includes: Occurrent

regulates,EntityToEntity
type: Property
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: MolecularEntity

hasGeneProduct
type: Property
comment: holds between a gene and a transcribed and/or translated product generated from it
domain includes: Gene
is part of: schema.biothings.io
range includes: GeneProduct

inPathwayWith
type: Property
comment: holds between two genes or gene products that are part of in the same biological pathway
domain includes: GeneOrGeneProduct
is part of: schema.biothings.io
range includes: GeneOrGeneProduct

inComplexWith
type: Property
comment: holds between two genes or gene products that are part of (or code for products that are part of) in the same macromolecular complex
domain includes: GeneOrGeneProduct
is part of: schema.biothings.io
range includes: GeneOrGeneProduct

inCellPopulationWith
type: Property
comment: holds between two genes or gene products that are expressed in the same cell type or population
domain includes: GeneOrGeneProduct
is part of: schema.biothings.io
range includes: GeneOrGeneProduct

geneAssociatedWithCondition
type: Property
comment: holds between a gene and a disease or phenotypic feature that the gene or its alleles/products may influence, contribute to, or correlate with
domain includes: Gene
is part of: schema.biothings.io
range includes: DiseaseOrPhenotypicFeature

treats
type: Property
comment: holds between a therapeutic procedure or chemical substance and a disease or phenotypic feature that it is used to treat
domain includes: Treatment
is part of: schema.biothings.io
range includes: DiseaseOrPhenotypicFeature

correlatedWith
type: Property
comment: holds between a disease or phenotypic feature and a measurable molecular entity that is used as an indicator of the presence or state of the disease or feature.
domain includes: DiseaseOrPhenotypicFeature
is part of: schema.biothings.io
range includes: MolecularEntity

hasBiomarker
type: Property
comment: holds between a disease or phenotypic feature and a measurable molecular entity that is used as an indicator of the presence or state of the disease or feature.
domain includes: DiseaseOrPhenotypicFeature
is part of: schema.biothings.io
range includes: MolecularEntity

biomarkerFor
type: Property
comment: holds between a measurable molecular entity and a disease or phenotypic feature, where the entity is used as an indicator of the presence or state of the disease or feature.
domain includes: MolecularEntity
is part of: schema.biothings.io
range includes: DiseaseOrPhenotypicFeature

expressedIn
type: Property
comment: holds between a gene or gene product and an anatomical entity in which it is expressed
domain includes: GeneOrGeneProduct
is part of: schema.biothings.io
range includes: AnatomicalEntity

expresses
type: Property
comment: holds between an anatomical entity and gene or gene product that is expressed there
domain includes: AnatomicalEntity
is part of: schema.biothings.io
range includes: GeneOrGeneProduct

hasPhenotype
type: Property
comment: holds between a biological entity and a phenotype, where a phenotype is construed broadly as any kind of quality of an organism part, a collection of these qualities, or a change in quality or qualities (e.g. abnormally increased temperature).
domain includes: BiologicalEntity
is part of: schema.biothings.io
range includes: DiseaseOrPhenotypicFeature

precedes
type: Property
comment: holds between two processes, where one completes before the other begins
domain includes: Occurrent
is part of: schema.biothings.io
range includes: Occurrent

subclassOf
type: Property
comment: holds between two classes where the domain class is a specialization of the range class
domain includes: OntologyClass
is part of: schema.biothings.io
range includes: OntologyClass