UNPKG

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This complex behavior has been broken down into six steps or sub behaviors: male response to hermaphrodite contact, backwards movement along her body, sharply turning in a ventral coil upon reaching the head or tail, continued backing until his tail contacts the vulva (vulval location), spicule insertion, and ejaculation into the hermaphrodite uterus. Each of these sub behaviors have been molecularly dissected and it has been found that two of these sub behaviors, male response to hermaphrodite contact and vulval location involve similar molecules. In particular these behaviors involve cell autonomous signaling through LOV-1 and PKD-2, which are homologs of human polycystin kidney disease (PKD) associated genes PC-1 and PC-2 respectively. Studies in C. elegans have shown that these genes likely have a sensory function rather than structural or development role in the cilia of male sensory neurons. 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