/**
 * @fileoverview Defines the core logic, schemas, and types for the `clinicaltrials_analyze_trends` tool.
 * @module src/mcp-server/tools/analyzeTrends/logic
 */
import { z } from "zod";
import { type RequestContext } from "../../../utils/index.js";
/**
 * Defines the types of analysis that can be performed.
 */
export declare const AnalysisTypeSchema: z.ZodEnum<["countByStatus", "countByCountry", "countBySponsorType", "countByPhase"]>;
/**
 * Zod schema for the `clinicaltrials_analyze_trends` tool input.
 */
export declare const AnalyzeTrendsInputSchema: z.ZodObject<Pick<{
    query: z.ZodOptional<z.ZodObject<{
        cond: z.ZodOptional<z.ZodString>;
        term: z.ZodOptional<z.ZodString>;
        locn: z.ZodOptional<z.ZodString>;
        titles: z.ZodOptional<z.ZodString>;
        intr: z.ZodOptional<z.ZodString>;
        outc: z.ZodOptional<z.ZodString>;
        spons: z.ZodOptional<z.ZodString>;
        id: z.ZodOptional<z.ZodString>;
    }, "strip", z.ZodTypeAny, {
        id?: string | undefined;
        cond?: string | undefined;
        term?: string | undefined;
        locn?: string | undefined;
        titles?: string | undefined;
        intr?: string | undefined;
        outc?: string | undefined;
        spons?: string | undefined;
    }, {
        id?: string | undefined;
        cond?: string | undefined;
        term?: string | undefined;
        locn?: string | undefined;
        titles?: string | undefined;
        intr?: string | undefined;
        outc?: string | undefined;
        spons?: string | undefined;
    }>>;
    filter: z.ZodOptional<z.ZodObject<{
        ids: z.ZodOptional<z.ZodArray<z.ZodString, "many">>;
        overallStatus: z.ZodOptional<z.ZodArray<z.ZodEnum<["ACTIVE_NOT_RECRUITING", "COMPLETED", "ENROLLING_BY_INVITATION", "NOT_YET_RECRUITING", "RECRUITING", "SUSPENDED", "TERMINATED", "WITHDRAWN", "UNKNOWN"]>, "many">>;
        geo: z.ZodOptional<z.ZodObject<{
            latitude: z.ZodNumber;
            longitude: z.ZodNumber;
            radius: z.ZodNumber;
            unit: z.ZodDefault<z.ZodEnum<["km", "mi"]>>;
        }, "strip", z.ZodTypeAny, {
            latitude: number;
            longitude: number;
            radius: number;
            unit: "km" | "mi";
        }, {
            latitude: number;
            longitude: number;
            radius: number;
            unit?: "km" | "mi" | undefined;
        }>>;
        advanced: z.ZodOptional<z.ZodString>;
    }, "strip", z.ZodTypeAny, {
        overallStatus?: ("ACTIVE_NOT_RECRUITING" | "COMPLETED" | "ENROLLING_BY_INVITATION" | "NOT_YET_RECRUITING" | "RECRUITING" | "SUSPENDED" | "TERMINATED" | "WITHDRAWN" | "UNKNOWN")[] | undefined;
        ids?: string[] | undefined;
        geo?: {
            latitude: number;
            longitude: number;
            radius: number;
            unit: "km" | "mi";
        } | undefined;
        advanced?: string | undefined;
    }, {
        overallStatus?: ("ACTIVE_NOT_RECRUITING" | "COMPLETED" | "ENROLLING_BY_INVITATION" | "NOT_YET_RECRUITING" | "RECRUITING" | "SUSPENDED" | "TERMINATED" | "WITHDRAWN" | "UNKNOWN")[] | undefined;
        ids?: string[] | undefined;
        geo?: {
            latitude: number;
            longitude: number;
            radius: number;
            unit?: "km" | "mi" | undefined;
        } | undefined;
        advanced?: string | undefined;
    }>>;
    fields: z.ZodOptional<z.ZodArray<z.ZodString, "many">>;
    sort: z.ZodOptional<z.ZodArray<z.ZodString, "many">>;
    pageSize: z.ZodOptional<z.ZodDefault<z.ZodNumber>>;
    pageToken: z.ZodOptional<z.ZodString>;
}, "filter" | "query"> & {
    analysisType: z.ZodUnion<[z.ZodEnum<["countByStatus", "countByCountry", "countBySponsorType", "countByPhase"]>, z.ZodArray<z.ZodEnum<["countByStatus", "countByCountry", "countBySponsorType", "countByPhase"]>, "many">]>;
}, "strip", z.ZodTypeAny, {
    analysisType: "countByStatus" | "countByCountry" | "countBySponsorType" | "countByPhase" | ("countByStatus" | "countByCountry" | "countBySponsorType" | "countByPhase")[];
    filter?: {
        overallStatus?: ("ACTIVE_NOT_RECRUITING" | "COMPLETED" | "ENROLLING_BY_INVITATION" | "NOT_YET_RECRUITING" | "RECRUITING" | "SUSPENDED" | "TERMINATED" | "WITHDRAWN" | "UNKNOWN")[] | undefined;
        ids?: string[] | undefined;
        geo?: {
            latitude: number;
            longitude: number;
            radius: number;
            unit: "km" | "mi";
        } | undefined;
        advanced?: string | undefined;
    } | undefined;
    query?: {
        id?: string | undefined;
        cond?: string | undefined;
        term?: string | undefined;
        locn?: string | undefined;
        titles?: string | undefined;
        intr?: string | undefined;
        outc?: string | undefined;
        spons?: string | undefined;
    } | undefined;
}, {
    analysisType: "countByStatus" | "countByCountry" | "countBySponsorType" | "countByPhase" | ("countByStatus" | "countByCountry" | "countBySponsorType" | "countByPhase")[];
    filter?: {
        overallStatus?: ("ACTIVE_NOT_RECRUITING" | "COMPLETED" | "ENROLLING_BY_INVITATION" | "NOT_YET_RECRUITING" | "RECRUITING" | "SUSPENDED" | "TERMINATED" | "WITHDRAWN" | "UNKNOWN")[] | undefined;
        ids?: string[] | undefined;
        geo?: {
            latitude: number;
            longitude: number;
            radius: number;
            unit?: "km" | "mi" | undefined;
        } | undefined;
        advanced?: string | undefined;
    } | undefined;
    query?: {
        id?: string | undefined;
        cond?: string | undefined;
        term?: string | undefined;
        locn?: string | undefined;
        titles?: string | undefined;
        intr?: string | undefined;
        outc?: string | undefined;
        spons?: string | undefined;
    } | undefined;
}>;
/**
 * TypeScript type inferred from the input schema.
 */
export type AnalyzeTrendsInput = z.infer<typeof AnalyzeTrendsInputSchema>;
/**
 * Zod schema for the analysis result.
 */
export declare const AnalysisResultSchema: z.ZodObject<{
    analysisType: z.ZodEnum<["countByStatus", "countByCountry", "countBySponsorType", "countByPhase"]>;
    totalStudies: z.ZodNumber;
    results: z.ZodRecord<z.ZodString, z.ZodNumber>;
}, "strip", z.ZodTypeAny, {
    analysisType: "countByStatus" | "countByCountry" | "countBySponsorType" | "countByPhase";
    totalStudies: number;
    results: Record<string, number>;
}, {
    analysisType: "countByStatus" | "countByCountry" | "countBySponsorType" | "countByPhase";
    totalStudies: number;
    results: Record<string, number>;
}>;
/**
 * Defines the structure for the analysis result.
 */
export type AnalysisResult = z.infer<typeof AnalysisResultSchema>;
/**
 * Zod schema for the output of the `clinicaltrials_analyze_trends` tool.
 */
export declare const AnalyzeTrendsOutputSchema: z.ZodObject<{
    analysis: z.ZodArray<z.ZodObject<{
        analysisType: z.ZodEnum<["countByStatus", "countByCountry", "countBySponsorType", "countByPhase"]>;
        totalStudies: z.ZodNumber;
        results: z.ZodRecord<z.ZodString, z.ZodNumber>;
    }, "strip", z.ZodTypeAny, {
        analysisType: "countByStatus" | "countByCountry" | "countBySponsorType" | "countByPhase";
        totalStudies: number;
        results: Record<string, number>;
    }, {
        analysisType: "countByStatus" | "countByCountry" | "countBySponsorType" | "countByPhase";
        totalStudies: number;
        results: Record<string, number>;
    }>, "many">;
}, "strip", z.ZodTypeAny, {
    analysis: {
        analysisType: "countByStatus" | "countByCountry" | "countBySponsorType" | "countByPhase";
        totalStudies: number;
        results: Record<string, number>;
    }[];
}, {
    analysis: {
        analysisType: "countByStatus" | "countByCountry" | "countBySponsorType" | "countByPhase";
        totalStudies: number;
        results: Record<string, number>;
    }[];
}>;
/**
 * TypeScript type inferred from the output schema.
 */
export type AnalyzeTrendsOutput = z.infer<typeof AnalyzeTrendsOutputSchema>;
/**
 * Performs a statistical analysis on a set of clinical trials matching the given criteria.
 * It fetches all studies (up to a limit) and aggregates data based on the specified analysis type.
 *
 * @param params - The validated input parameters for the tool.
 * @param context - The request context for logging and tracing.
 * @returns A promise that resolves with the structured analysis results.
 * @throws {McpError} If the query returns more studies than the analysis limit.
 */
export declare function analyzeTrendsLogic(params: AnalyzeTrendsInput, context: RequestContext): Promise<AnalyzeTrendsOutput>;