import { IIdentifier, ICodeableConcept, IElement, IReference, IAge, IPeriod, IRange, IAnnotation, IAllergyIntoleranceReaction, AllergyIntoleranceTypeType, AllergyIntoleranceCategoryType, AllergyIntoleranceCriticalityType } from 'fhirtypes/dist/r4';
import { IAllergyIntolerance, IOperationOutcome } from 'fhirtypes/dist/r4';
import { DomainResource, IValidatable, ISerializable } from '../base';
/**
 * @version R4 (v4.0.1)
 * @summary FHIR® Specification by HL7®
 * @description Class for AllergyIntolerance Resource
 * @property {string} resourceType
 * @property {IIdentifier[]} identifier
 * @property {ICodeableConcept} clinicalStatus
 * @property {ICodeableConcept} verificationStatus
 * @property {AllergyIntoleranceTypeType} type
 * @property {IElement} _type
 * @property {AllergyIntoleranceCategoryType[]} category
 * @property {IElement[]} _category
 * @property {AllergyIntoleranceCriticalityType} criticality
 * @property {IElement} _criticality
 * @property {ICodeableConcept} code
 * @property {IReference} patient
 * @property {IReference} encounter
 * @property {string} onsetDateTime
 * @property {IElement} _onsetDateTime
 * @property {IAge} onsetAge
 * @property {IPeriod} onsetPeriod
 * @property {IRange} onsetRange
 * @property {string} onsetString
 * @property {IElement} _onsetString
 * @property {string} recordedDate
 * @property {IElement} _recordedDate
 * @property {IReference} recorder
 * @property {IReference} asserter
 * @property {string} lastOccurrence
 * @property {IElement} _lastOccurrence
 * @property {IAnnotation[]} note
 * @property {IAllergyIntoleranceReaction[]} reaction
 * @author Roberto Araneda Espinoza
 */
export declare class AllergyIntolerance extends DomainResource implements IAllergyIntolerance, IValidatable, ISerializable {
    /**
     * @description The type of resource
     */
    resourceType?: string | undefined;
    /**
     * @description Business identifiers assigned to this AllergyIntolerance by the performer or other systems which remain constant as the resource is updated and propagates from server to server.
     */
    identifier?: IIdentifier[];
    /**
     * @description The clinical status of the allergy or intolerance.
     */
    clinicalStatus?: ICodeableConcept;
    /**
     * @description Assertion about certainty associated with the propensity, or potential risk, of a reaction to the identified substance (including pharmaceutical product).
     */
    verificationStatus?: ICodeableConcept;
    /**
     * @description Identification of the underlying physiological mechanism for the reaction risk.
  allergy | intolerance.
     */
    type?: AllergyIntoleranceTypeType;
    /**
     * @description Extensions for type
     */
    _type?: IElement;
    /**
     * @description Category of the identified substance.
  food | medication | environment | biologic.
     */
    category?: AllergyIntoleranceCategoryType[];
    /**
     * @description Extensions for category
     */
    _category?: IElement[];
    /**
     * @description Estimate of the potential clinical harm, or seriousness, of the reaction to the identified substance.
  low | high | unable-to-assess.
     */
    criticality?: AllergyIntoleranceCriticalityType;
    /**
     * @description Extensions for criticality
     */
    _criticality?: IElement;
    /**
     * @description Code for an allergy or intolerance statement (either a positive or a negated/excluded statement).  This may be a code for a substance or pharmaceutical product that is considered to be responsible for the adverse reaction risk (e.g., "Latex"), an allergy or intolerance condition (e.g., "Latex allergy"), or a negated/excluded code for a specific substance or class (e.g., "No latex allergy") or a general or categorical negated statement (e.g.,  "No known allergy", "No known drug allergies").  Note: the substance for a specific reaction may be different from the substance identified as the cause of the risk, but it must be consistent with it. For instance, it may be a more specific substance (e.g. a brand medication) or a composite product that includes the identified substance. It must be clinically safe to only process the 'code' and ignore the 'reaction.substance'.  If a receiving system is unable to confirm that AllergyIntolerance.reaction.substance falls within the semantic scope of AllergyIntolerance.code, then the receiving system should ignore AllergyIntolerance.reaction.substance.
     */
    code?: ICodeableConcept;
    /**
     * @description The patient who has the allergy or intolerance.
     */
    patient: IReference;
    /**
     * @description The encounter when the allergy or intolerance was asserted.
     */
    encounter?: IReference;
    /**
     * @description Estimated or actual date,  date-time, or age when allergy or intolerance was identified.
     */
    onsetDateTime?: string;
    /**
     * @description Extensions for onsetDateTime
     */
    _onsetDateTime?: IElement;
    /**
     * @description Estimated or actual date,  date-time, or age when allergy or intolerance was identified.
     */
    onsetAge?: IAge;
    /**
     * @description Estimated or actual date,  date-time, or age when allergy or intolerance was identified.
     */
    onsetPeriod?: IPeriod;
    /**
     * @description Estimated or actual date,  date-time, or age when allergy or intolerance was identified.
     */
    onsetRange?: IRange;
    /**
     * @description Estimated or actual date,  date-time, or age when allergy or intolerance was identified.
     */
    onsetString?: string;
    /**
     * @description Extensions for onsetString
     */
    _onsetString?: IElement;
    /**
     * @description The recordedDate represents when this particular AllergyIntolerance record was created in the system, which is often a system-generated date.
     */
    recordedDate?: string;
    /**
     * @description Extensions for recordedDate
     */
    _recordedDate?: IElement;
    /**
     * @description Individual who recorded the record and takes responsibility for its content.
     */
    recorder?: IReference;
    /**
     * @description The source of the information about the allergy that is recorded.
     */
    asserter?: IReference;
    /**
     * @description Represents the date and/or time of the last known occurrence of a reaction event.
     */
    lastOccurrence?: string;
    /**
     * @description Extensions for lastOccurrence
     */
    _lastOccurrence?: IElement;
    /**
     * @description Additional narrative about the propensity for the Adverse Reaction, not captured in other fields.
     */
    note?: IAnnotation[];
    /**
     * @description Details about each adverse reaction event linked to exposure to the identified substance.
     */
    reaction?: IAllergyIntoleranceReaction[];
    /**
     * @description Returns a JSON representation of the model
     * @returns {Record<string, any>}
     */
    toJson(): Record<string, any>;
    /**
     * @description Returns a string representation of the model
     * @returns {string}
     */
    toString(): string;
    /**
     * @description Returns a pretty string representation of the model
     * @returns {string}
     */
    toPrettyString(): string;
    /**
     * @description Returns a serialized string representation of the model
     * @returns {string}
     */
    serialize(): string;
    /**
     * @description Validates the model
     * @returns {isValid: boolean, operationOutcome: IOperationOutcome}
     */
    validate(): {
        isValid: boolean;
        operationOutcome: IOperationOutcome;
    };
    constructor(args?: IAllergyIntolerance);
}